Ethyl Cellulose (EC)
SidleyCel® Ethyl Cellulose (EC) is white or light gray powder or granule. It is odorless, tasteless, insoluble in water but easily soluble in various organic solvents.
SidleyCel® Ethyl Cellulose (EC) is mainly used as tablet binder to increase the hardness and reduce the fragility of tablets. As film-forming agent, it can improve the
appearance of the tablet, isolate odor, keep away moisture and deterioration of drug, and prolong the shelf life. It also can be used as ink binder, helps to form a wear-resistant ink film. SidleyCel® EC has good compatibility with various solvents, pigments and other resins.
Ethyl Cellulose did not dissolve in water, but soluble in many organic solvents were used as tablets, granules of the adhesive, can increase the hardness of tablets to reduce friability tablets, it can be used as film-forming agent to improve the appearance of tablets, isolated taste, to avoid the failure of water-sensitive drugs to prevent the influx of metamorphic change agents, promoting the safe storage of tablets, but also can be used as reinforcing material for Sustained Release Tablets.
The solubility of cellulose after etherification changes significantly, and can be dissolved in water, dilute acid, dilute base or organic solvent. The solubility mainly depends on three factors: (1) The characteristics of the groups introduced in the etherification process, the larger the group introduced, the lower the solubility, the stronger the polarity of the group introduced, and the more soluble the cellulose ether is in water; (2) The degree of substitution and the distribution of etherification groups in macromolecules. Most cellulose ethers can only be dissolved in water under certain degree of substitution, and the degree of substitution is between 0 and 3. (3) the degree of polymerization of cellulose ether, the higher the degree of polymerization, the more difficult to dissolve; The lower the degree of polymerization, the wider the range of substitution degree soluble in water. Cellulose ether varieties, excellent performance, widely used in construction, cement, petroleum, food, textile, detergent, paint, medicine, paper and electronic components industry.